First Synthesis of a Representative, Natural Pterin
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چکیده
Glycosylation of N-(N,N-dimethylaminomethylene)-1’-O-(4-methoxybenzyl)-3-[2-(4-nitrophenyl)ethyl]biopterin (14) with the novel donor 4,6-di-O-acetyl-2,3-di-O-(4-methoxy benzyl)αD -glucopyranosyl bromide (19) in the presence of silver triflate and tetramethylurea predominantly afforded the corresponding α-D-glucopyranoside (20a), from which 2’-O-(α-D-glucopyranosyl)biopterin (1) was obtained by the successive removal of the protecting groups.
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تاریخ انتشار 2010